In this lesson, students use the app, Powers of Minus Ten Bone, to discover the innerworkings of cells and their organelles. Exploration of the app is guided with the use of a scaffolded worksheet as well as a class discussion. Later in the lesson, student groups are assigned a specific organelle and use the information contained in the app to draw similarities and differences between the buildings in a city to the organelles inside a cell. Students will construct a clay model of an organelle as well as a model of a city building. Finally, student groups are asked to present their work via a class presentation followed by a creative writing assignment.